Formation of enzyme-substrate complex (ES) is the first step in catalysed reactions. Describe the other steps till the formation of product.



Step 1:


It involves the formation of E-S substrate complex, formed when enzyme binds to substrate at active site.


Step2: Transient phase



• The structure of substrate changes, during this very high energy of activation is involved.


Step3: Formation phase



• Finally the product gets formed.


• Enzyme gets free to bind with new substrate.


• Potential energy of the system declines.


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