State and explain in brief the four major factors, which are causes of disease.

Physical inactivity. - It is one of the main reasons for many diseases

Raised cholesterol. It leads to blocked heart and arteries. It causes damage to cardiac and nervous system

Unhealthy diet - Unhealthy diet leads to malnutrition and excess of nutrition. It damages the body parts and bodily functions

Raised blood glucose. It leads to diabetes and a person has to rely on medicine throughout life.