Q5 of 19 Page 125

Which property of DNA double helix led Watson and Crick to hypothesise semi-conservative mode of DNA replication? Explain.

The property of DNA double helix that led Watson and Crick to hypothesise semi-conservative of DNA replication was that the two strands in the DNA are complementary and anti-parallel based on their base sequences. They suggested that the two strands would separate and act as a template for the synthesis of new complementary strands. After the replication, each DNA molecule would have one parent strand and one newly synthesized daughter strand.


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3

If the sequence of one strand of DNA is written as follows:

5'-ATGCATGCATGCATGCATGCATGCATGC-3'


Write down the sequence of complementary strand in 5' 3' direction.

 4

If the sequence of the coding strand in a transcription unit is written as follows: 5'-ATGCATGCATGCATGCATGCATGCATGC-3'

Write down the sequence of mRNA.

 6

Depending upon the chemical nature of the template (DNA or RNA) and the nature of nucleic acids synthesized from it (DNA or RNA), list the types of nucleic acid polymerases.

 7

How did Hershey and Chase differentiate between DNA and protein in their experiment while proving that DNA is the genetic material?