Q5 of 53 Page 29

In sickle cell anaemia glutamic acid is replaced by valine. Which one of the following triplets codes for valine?

GUG is the triplet that codes for valine.


In sickle cell anaemia the Glutamic acid (Glu) is substituted by Valine (Val) at the sixth position of the beta globin chain of haemoglobin molecule. That is a single base substitution at the sixth codon of beta globin gene from GAG to GUG.

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