Q11 of 57 Page 85

How is a mature, functional insulin hormone different from its prohormone form?

- Pro insulin contains 3 chains of polypeptides i.e. A, B & chain C.


Chain A have 21 amino acids, B contains 30 amino acids & chain c consists of 33 amino acids.


When C-peptide is removed and cut, A & B peptide chains are joined by disulfide bonds, mature, functional insulin is formed.


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