Q14 of 30 Page 1

Write the function of adenosine deaminase enzyme. State the cause of ADA deficiency in humans. Mention a possible permanent cure for a ADA deficiency patient.

• The enzyme adenosine deaminase (ADA) is very important for the proper functioning of the immune system.


• In humans, it is caused due to the deletion of the gene for adenosine deaminase which codes for ADA.


• Gene therapy permanently cures ADA deficiency.


• For permanent cure, at early embryonic stages, the functional ADA gene is inserted into the cells.


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