Mention how is mutation theory of Hugo de Vries different from Darwin’s theory of natural selection.

According to Hugo de Vries, new species arise due to single step large mutation whereas according to Darwin, evolution occurs gradually by the method of natural selection.

Darwin believed that minor variations are the cause of the evolution and his theory is based on the natural selection.

On the other part, Hugo de Vries believed that mutation is the cause of evolution, and his theory is based on the mutation.