Q10 of 49 Page 1

Name the group of cells the HIV enters after getting into the human body. What happens in these cells and what are these cells subsequently referred as? Name the next group of cells the HIV attacks from here.

• HIV stands for human immunodeficiency virus. HIV causes AIDS (Acquired Immune-Deficiency syndrome).


• When the HIV gets inside a person’s body, it attacks his/her immune system and enters into the macrophages and replicates its RNA genome and forms viral DNA.


• Then this viral DNA gets incorporated in the host cell’s DNA and directs the infected cells to produce viral particles.


• This goes on over and over and the viral particle production continues making the macrophages act like an HIV-factory.


• Here on the virus enters the helper T cells or the T-lymphocytes.


• Due to the repeated attack, the number of helper T-cells decreases drastically.


• As a result, the person’s immunity gets compromised and they start suffering from even minor infections that the body could otherwise have recovered from.


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