Q13 of 49 Page 1

A. List the two methodologies which were involved in human genome project. Mention how they were used.

B. Expand ‘YAC’ and mention what was it used for.

A. Two methodologies of HGP are:


i. Expressed Sequence Tags (EST's): In this method all the genes are identified which are expressed as RNA.


ii. Sequence annotation: In this method the whole set of genomes that contains all the coding and non-coding sequences are sequenced and later assigning different regions in the sequence with functions.


B. 'YAC' stands for Yeast Artificial Chromosome. It is used as a cloning vector for cloning DNA fragments in suitable host.


More from this chapter

All 49 →
11

A. Can a plant flowering in Mumbai be pollinated by pollen grains of the same species growing in New Delhi? Provide explanations to your answer.

B. Draw the diagram of a pistil where pollination has successfully occurred. Label the parts involved in reaching the male gametes to its desired destination.

 12

Both Haemophilia and Thalassemia are blood related disorders in humans. Write their causes and the difference between the two. Name the category of genetic disorder they both come under.

 14

Write the characteristics of Ramapithecus, Dryopithecus and Neanderthal man.

 15

Name a human disease, its causal organism, symptoms (any three) and vector, spread by intake of water and food contaminated by human faucal matter.