Q18 of 43 Page 1

Explain the Hardy-Weinberg principle.

The Hardy-Weinberg principle states that the frequency of occurrence of alleles of a gene is constant from generation to generation and it is expressed as where p and q represent the frequency of different alleles.


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Write the palindromic nucleotide sequence that EcoRI reads, and indicate the site of its action.

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A normal couple has a colour-blind child, whereas a child suffering from thalassemia is born to normal parents. Compare the pattern of inheritance of these two traits in the said cases. State the reasons how is it possible.

OR


(a) State the reasons for which Hershey and Chase carried out their


experiments.


(b) Answer the following questions based on the experiments of


Hershey and Chase:


(i) Name the different radioactive isotopes they used, and explain how they used them.


(ii) Why did they need to agitate and spin their culture?


(iii) Write their observations and the conclusions they arrived at.