Q10 of 71 Page 40

Name a few enzymes involved in DNA replication other than DNA polymerase and ligase. Name the key functions for each of them.

The few enzymes involved in DNA replication other than DNA polymerase and ligase are:

1. Helicases: These are the enzymes which separate the two DNA strands at the replication fork using energy. These enzymes are also called as helix destabilizing enzyme.


2. DNA Clamp: This enzyme is used to promote the replication of the DNA. It binds the DNA polymerase enzyme to the template strand and prevents it from disassociating. It is also known as sliding Clamp.


3. Single Strand Binding Proteins:These enzymes prevent the single strand of DNA to get digested by the nucleases. It also prevents the formation of secondary structure.


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