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6. Molecular Basis of Inheritance
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Q19 of 71 Page 41

During in vitro synthesis of DNA, a researcher used 2’, 3’ – dideoxy cytidine triphosphate as raw nucleotide in place of 2’-deoxy cytidine. What would be the consequence?

Polymerisation would not take place as the 3’OH group on the sugar is not present to add a nucleotide for forming ester bonds.


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What background information did Watson and Crick have made available for developing a model of DNA? What was their contribution?

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