In an experiment, DNA is treated with a compound which tends to place itself amongst the stacks of nitrogenous base pairs. As a result of this, the distance between two consecutive base increases. from 0.34nm to 0.44 nm calculate the length of DNA double helix (which has 2×109 bp) in the presence of saturating amount of this compound.

During DNA replication, why is it that the entire molecule does not open in one go? Explain replication fork. What are the two functions that the monomers (d NTPs) play?

Retroviruses do not follow central Dogma. Comment.

What would happen if histones were to be mutated and made rich in acidic amino acids such as aspartic acid and glutamic acid in place of basic amino acids such as lysine and arginine?

Recall the experiments done by Frederick Griffith, Avery, MacLeod and McCarty, where DNA was speculated to be the genetic material. If RNA, instead of DNA was the genetic material, would the heat killed strain of Pneumococcus have transformed the R-strain into virulent strain? Explain.