The total number of genes in humans is far less (< 25,000) than the previous estimate (up to 1,40,000 gene). Comment.
The total number of genes in humans is far less (< 25,000) than the previous estimate (up to 1,40,000 gene) because of the presence of large portions of repetitive sequencing regions in the human genome. These are the stretches of the DNA sequence that are repeated numerous times hence the non-repetitive gene count is less, if the repetitive portions are not added. These stretches have no coding functions but make it possible to understand chromosome structure, dynamics and evolution.
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