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6. Molecular Basis of Inheritance
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Q23 of 71 Page 41

Comment on the utility of variability in number of tandem repeats during DNA finger printing.

Tandems is a chromosomal region in which a small stretch of DNA sequence is repeated numerous times in a single location. It forms a pattern of bands which is unique for each individual and is used in DNA fingerprinting in forensic department.


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21

What are the functions of (i) methylated guanosine cap, (ii) poly-A “tail” in a mature on RNA?

22

Do you think that the alternate splicing of exons may enable a structural gene to code for several isoproteins from one and the same gene? If yes, how? If not, why so?

1

Give an account of Hershey and Chase experiment. What did it conclusively prove? If both DNA and proteins contained phosphorus and sulphur do you think the result would have been the same?

2

During the course of evolution why DNA was chosen over RNA as genetic material? Give reasons by first discussing the desired criteria in a molecule that can act as genetic material and in the light of biochemical differences between DNA and RNA.

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6. Molecular Basis of Inheritance
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