Why has the Indian Government set up the organization named GEAC?Give any two reasons.

OR

Give a schematic representation of the transformation of a pro-insulininto insulin.

The full form of GEAC is Genetic Engineering Appraisal Committee and was established in 1989

Functions of GEAC are –

•It is responsible for appraisal of activities involving large scale use of hazardous mircooragnisms and recombinants in research

•It is also responsible for appraisal of proposals relating to release of genetically engineered (GE) organism and products into the environment

OR

Proinsulin is a single polypeptide chain composed of the B and A subunits of insulin joined by the C-peptide region. Preproinsulin is converted into proinsulin by signal peptidases, which remove its signal peptide from its N-terminus. Finally, proinsulin is converted into the bioactive hormone insulin by removal of the C-peptide.